Nole overcame Nishikori to clinch an important win on the Manolo Santana Stadium.
Novak Djokovic, the 10th seed, opened his Mutua Madrid Open campaign on Monday with a straight sets win over Japan’s Kei Nishikori.
The two-time titlist (2011, 2016) took one hour and 58 minutes to secure a 7-5, 6-4 victory.
Novak won 72 per cent of points behind his first serve, breaking the fellow Uniqlo colleague three times and saving five of six break points he faced to improve stats in their ATP H2H rivalry to 12-2.
“It was strange, I must admit, playing Kei in the first round,” Djokovic said. “Our rankings dropped due to injuries and everything else that was happening the last year. I’ve played Kei on big occasions, in many of the big tournaments, finals and semi-finals. It was different to play him in the first round. It was a big test for both of us. I’m glad that match went my way, but it could have gone his way as well. It was a very few points that really decided a winner today. I managed to play the right shots in the important moments. In both first and second set I made breaks, to win both sets at the really final stages.”
Match statistics: aces (6-1), double faults (5-1), winners (26-21), unforced errors (33-26), total points won (81-76).
For a place in the last 16, Novak will play Kyle Edmund (ATP no.22, GBR) on Wednesday.